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Sox-2 Antibody
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Product OverviewAntibody Target: Sox-2
Alternative Name: Sox2, Sox 2, SRY-box containing gene 2, sex determining region Y box-2, SRY related HMG box 2, Transcription factor SOX 2
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 301 of human Sox2
Accession#: CAA83435
Gene ID: 6657
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-Sox-2polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.
Purification: Affinity purified
Species Reactivity: human, mouse, rat, pig, bovine, dog, sheep
Application: Western blot
Application & Usage: Western blotting (0.5-1 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been tested. The antibody detects ~35kDa of Sox2 in samples from mouse origins.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Sox genes encode for transcriptional regulators that are involved in the early embryonic develpoment and in the determination of cell fate. Sox2 is also known as SRY (sex determining region Y)-box2, contain genes that encode for the HMG-box domain that is responsible for DNA binding activity. Mutation of Sox2 genes is link to optic nerve hypoplasia and anophthalmia, a severe form of eye deformity.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans. |