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NTAL/LAB Antibody
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Product OverviewAntibody Target: NTAL/LAB
Alternative Name: HSPC046 , LAB , LAT2 , NTAL, WBSCR15, WBSCR5 , WSCR5
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding amino acid 187 of rat NTAL
Accession#: Q8CGL2
Gene ID: 317676
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification: Affinity purified
Species Reactivity: rat
Application: Western blot
Application & Usage: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects a 22 kDa rat NTAL/LAB. Other species have not been determined.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Non-T cell Activation Linker (NTAL) is also known as linker for activation of B cells (LAB), is a transmembrane adaptor protein. NTAL is expressed in B cells, mast cells, monocytes and NK cells. When NTAL is tyrosine phosphorylated, it recruits signalling molecules such as Grb2, Gab2 and c-Cbl into receptor-signalling complexes. Mutation in the NTAL gene may cause Williams-Beuren syndrome, a rare genetic disorder.
Handling: The antibody solution should be gently mixed before use.
Usage: For Research Use Only! Not to be used in humans.
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