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AL 8810 methyl ester
Cayman Chemical Item Number 10008370
Description
AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor.1↗ AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular PG compounds such as latanoprost2↗ and travoprost.3↗ The pharmacology of AL 8810 methyl ester has not been published.
Formal Name 9α,15R-dihydroxy-11β-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid, methyl ester
CAS Number 1176541-11-9
Molecular Formula C25H33FO4
Formula Weight 416.5
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES COC(=O)CCC/C=C\CC1C(O)C[C@H](F)[C@@H]1\C=C\[C@H](O)C1Cc2ccccc2C1
InCHI Code 1S/C25H33FO4/c1-30-25(29)11-5-3-2-4-10-21-20(22(26)16-24(21)28)12-13-23(27)19-14-17-8-6-7-9-18(17)15-19/h2,4,6-9,12-13,19-24,27-28H,3,5,10-11,14-16H2,1H3/b4-2-,13-12+/t20-,21-,22+,23+,24+/m1/s1
InCHI Key SUQUNXDCROKALM-ZOXVUOEWSA-N |