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N-Cyclohexanecarbonyltetradecylamine
Cayman Chemical Item Number 10008317
Description
Numerous analogs of fatty acyl ethanolamides potentiate the intrinsic biological activity of endocannabinoids.1↗ This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty acid amide hydrolase (FAAH) within the neurons. 2↗ However, Ueda, et al. has recently cloned another amidase, the acidic PEAase that promotes the hydrolysis of palmitoylethanolamide.3↗ N-Cyclohexanecarbonyltetradecylamine is an analog of N-cyclohexanecarbonyl-pentadecylamine, a selective inhibitor of acidic PEAase with an IC50 of 4.5 µM, that contains 1 less carbon in the alkyl chain.4↗ The biological activity of N-cyclohexanecarbonyltetradecylamine has not been documented.
Formal Name N-tetradecyl-cyclohexanecarboxamide
CAS Number 1215071-05-8
Molecular Formula C21H41NO
Formula Weight 323.6
Formulation A crystalline solid
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCCCCCCCCCCCCNC(=O)C1CCCCC1
InCHI Code 1S/C21H41NO/c1-2-3-4-5-6-7-8-9-10-11-12-16-19-22-21(23)20-17-14-13-15-18-20/h20H,2-19H2,1H3,(H,22,23)
InCHI Key MIHNEWQWEUOBSN-UHFFFAOYSA-N |