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GW 610
Cayman Chemical Item Number 10008313
Description
GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0.1 nM) was observed.1↗ Potent and selective activity was also observed in the NCI 60 human cancer cell line panel. In contrast with previously reported 2-(4-aminophenyl)benzothiazoles, GW 610 is not reliant on induction of cytochrome P 1A1 (CYP1A1) expression for antitumor activity.
Synonyms NSC 721648
Formal Name 2-(3,4-dimethoxyphenyl)-5-fluoro-benzothiazole
CAS Number 872726-44-8
Molecular Formula C15H12FNO2S
Formula Weight 289.3
Formulation A crystalline solid
Purity ≥98%
λmax 223, 324 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES COc1cc(ccc1OC)c1nc2cc(F)ccc2s1
InCHI Code 1S/C15H12FNO2S/c1-18-12-5-3-9(7-13(12)19-2)15-17-11-8-10(16)4-6-14(11)20-15/h3-8H,1-2H3
InCHI Key ZRLSVQBGBBYEAZ-UHFFFAOYSA-N |