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N-acetyl-2-carboxy BenzenesulfonamideExclusive
Cayman Chemical Item Number 10008284
Description N-acetyl-2-carboxy Benzenesulfonamide is a is a structural analog of aspirin that acts as a non-selective inhibitor of cyclooxygenase (COX) with a COX-2 selectivity index of 0.23.1↗ In vitro studies showed that N-acetyl-2-carboxy Benzenesulfonamide is a more potent inhibitor of COX-1/COX-2 with IC50 values of 0.06 µM and 0.25 µM, respectively, than aspirin with IC50 values of 0.35 µM and 2.4 µM, respectively.
Formal Name 2-[(acetylamino)sulfonyl]-benzoic acid
CAS Number 849067-18-1
Molecular Formula C9H9NO5S
Formula Weight 243.2
Formulation A crystalline solid
Purity ≥98%
λmax 206, 224, 276 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CC(=O)NS(=O)(=O)c1ccccc1C(=O)O
InCHI Code 1S/C9H9NO5S/c1-6(11)10-16(14,15)8-5-3-2-4-7(8)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13)
InCHI Key ADVANFQVCYCSNR-UHFFFAOYSA-N |