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Linolenic Acid ethyl ester
Cayman Chemical Item Number 10008199
Description
α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation.1↗ Linolenic acid ethyl ester (LAEE) is a neutral, more lipophilic form of the free acid that can be used as an exogenous source of α-linolenic acid. This ethanol metabolite may contribute to ethanol-induced hepatic fibrogenesis through stimulation of intracellular signaling pathways in hepatic stellate cells (HSC). LAEE increases cyclin E expression and Cdk2 activity as well as increases ERK and JNK activity.2↗
Synonyms LAEE Ethyl α-Linolenate
Formal Name 9Z,12Z,15Z-octadecatrienoic acid, ethyl ester
CAS Number 1191-41-9
Molecular Formula C20H34O2
Formula Weight 306.5
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CC/C=C\C/C=C\C/C=C\CCCCCCCC(OCC)=O
InCHI Code 1S/C20H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-4-2/h5-6,8-9,11-12H,3-4,7,10,13-19H2,1-2H3/b6-5-,9-8-,12-11-
InCHI Key JYYFMIOPGOFNPK-AGRJPVHOSA-N |