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FABP2 (rat recombinant)
Cayman Chemical Item Number 10007938
Description
Source:recombinant N-terminal hexahistidine-tagged protein expressed in E. coli · Mr:19.3 kDa · Protein concentration:1.0 mg/ml · Fatty acid binding protein-2 (FABP2) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids.1↗ Members of this protein family exhibit high affinity for small lipophilic ligands and were named according to the tissue from which they were initially isolated.1↗ Studies suggest that FABPs are involved in the uptake and metabolism of fatty acids, in the maintenance of cellular membrane fatty acid levels, in intracellular trafficking of these substrates, in the modulation of specific enzymes of lipid metabolic pathways, and in the modulation of cell growth and differentiation.2↗ FABP family members have highly conserved three dimensional structures and 22-73% amino acid sequence similarity. FABP2 is composed of ten antiparallel b strands forming a barrel that binds the ligand in a bent confirmation. FABP2 polymorphism has been suggested to be associated with gender specific obesity and increased risk of diabetes.1↗
Synonyms Intestinal-FABP
I-FABP
Fatty Acid Binding Protein 2
Formulation A solution in 50 mM sodium phosphate, pH 7.2, containing 20% glycerol, 100 mM sodium chloride, and 1 mM DTT
Purity ≥95%
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere |