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D-erythro-Sphingosine C-20
Cayman Chemical Item Number 10007903
Description
Sphingosines are long-chain base precursors of cellular sphingolipids used directly in the synthesis of ceramide, which in combination with sialic acid forms ganglioside. Sphingosine can exist in four stereoisomers, however only D-erythro-sphingosine occurs naturally. Compared to other sphingolipids throughout the body, which are predominantly composed of C-18 sphingosine, only central nervous system (CNS) gangliosides contain significant amounts of D-erythro-sphingosine C-20.1↗,2↗ The concentration of D-erythro-sphingosine C-20 within mammalian brain gangliosides apparently increases with developmental maturation.1↗,2↗ Furthermore, the ratio of C-18 to C-20 sphingosine in the brain is thought to be related to some nervous system degeneration processes.1↗,2↗
Formal Name 2S-amino-4E-eicosene-1,3R-diol
CAS Number 6918-49-6
Molecular Formula C20H41NO2
Formula Weight 327.6
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES OC[C@H](N)[C@H](O)/C=C/CCCCCCCCCCCCCCC
InCHI Code 1S/C20H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)19(21)18-22/h16-17,19-20,22-23H,2-15,18,21H2,1H3/b17-16+/t19-,20+/m0/s1
InCHI Key HTJSZHKGNMXZJN-YIVRLKKSSA-N |