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8,11,14-Eicosatriynoic Acid
Cayman Chemical Item Number 10007900
Description 8,11,14-Eicosatriynoic acid is an inhibitor of prostaglandin and leukotriene biosynthesis as well as arachidonic acid induced platelet aggregation.1↗ It inhibits cyclooxygenase (IC50 = 14 µM), human 12-lipoxygenase (IC50 = 0.46 µM), 5-lipoxygenase (IC50 = 25 µM) and the actions of slow-reacting substance of anaphylaxis (SRS-A) (IC50 = 10 µM).2↗,3↗
Synonyms 8,11,14-ETI
Formal Name 8,11,14-eicosatriynoic acid
CAS Number 34262-64-1
Molecular Formula C20H28O2
Formula Weight 300.4
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCCCC#CCC#CCC#CCCCCCCC(O)=O
InCHI Code 1S/C20H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-5,8,11,14-19H2,1H3,(H,21,22)
InCHI Key QLLIWTBTVOPGCM-UHFFFAOYSA-N |