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N-butyryl-L-Homoserine lactone
Cayman Chemical Item Number 10007898
Description Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and cellular metabolism.1↗ The diverse applications of this molecule include regulation of virulence in general, infection prevention, and formation of biofilms.2↗,3↗,4↗,5↗,6↗,7↗
Synonyms C4-HSL
Formal Name N-[(3S)-tetrahydro-2-oxo-3-furanyl]-butanamide
CAS Number 67605-85-0
Molecular Formula C8H13NO3
Formula Weight 171.2
Formulation A crystalline solid
Purity ≥95%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCC(=O)N[C@H]1CCOC1=O
InCHI Code 1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)/t6-/m0/s1
InCHI Key VFFNZZXXTGXBOG-LURJTMIESA-N |