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α-CEHC
Cayman Chemical Item Number 10007705
Description
Molecules having vitamin E antioxidant activity include four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ).1↗ α-Tocopherol is the major lipid soluble antioxidant in vivo and protects against lipid peroxidation.2↗ α-CEHC is the major urinary metabolite of α-tocopherol following vitamin E supplementation.3↗ The concentration of α-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-α-tocopherol. About one-third of the α-CEHC circulating in the blood is present as a glucuronide conjugate.4↗ α-CEHC was only excreted when a threshold concentration of 7-9 µmol α-tocopherol/g total lipid in plasma was exceeded. Therefore, excretion of α-CEHC may be considered to be a marker of optimum vitamin E intake.5↗
Formal Name (S)-3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-propanoic acid
CAS Number 507441-93-2
Molecular Formula C16H22O4
Formula Weight 278.3
Formulation A crystalline solid
Purity ≥98%
λmax 206, 291 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CC1=C(O[C@@](CCC(O)=O)(C)CC2)C2=C(C)C(O)=C1C
InCHI Code 1S/C16H22O4/c1-9-10(2)15-12(11(3)14(9)19)5-7-16(4,20-15)8-6-13(17)18/h19H,5-8H2,1-4H3,(H,17,18)/t16-/m0/s1
InCHI Key AXODOWFEFKOVSH-INIZCTEOSA-N |