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N-(3-hydroxyphenyl)-Arachidonoyl amideExclusive
Cayman Chemical Item Number 10007704
Description
N-(3-hydroxyphenyl)-Arachidonoyl amide (3-HPA) is an analog of AM404 (N-(4-hydroxyphenyl)-arachidonoyl amide), which is a selective inhibitor of carrier-mediated transport of arachidonoyl ethanolamide (AEA).1↗ 3-HPA is metabolized by both cyclooxygenase-1 (COX-1) and COX-2 and was found to selectively and irreversibly inhibit COX-2 with an IC50 value of 2 µM.2↗
Synonyms 3-HPAA
Formal Name N-(3-hydroxyphenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
CAS Number 183718-75-4
Molecular Formula C26H37NO2
Formula Weight 395.6
Formulation A solution in ethanol
Purity >98%
λmax 246, 282 nm
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)Nc
InCHI Code 1S/C26H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-26(29)27-24-20-19-21-25(28)23-24/h6-7,9-10,12-13,15-16,19-21,23,28H,2-5,8,11,14,17-18,22H2,1H3,(H,27,29)/b7-6-,10-9-,13-12-,16-15-
InCHI Key ZWSMMQKRRVRXBA-DOFZRALJSA-N |