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2,3-dinor Thromboxane B1
Cayman Chemical Item Number 10006330
Description
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.1↗ In rats and rabbits, 2,3-dinor TXB1 has been identified as another urinary metabolite of TXB2.2↗,3↗ However in human urine, only trace amounts of 2,3-dinor TXB1 have been identified.2↗ In rats, 2,3-dinor TXB1 is excreted at a much higher rate than 2,3-dinor TXB2 (19.2 ± 4.9 ng/24 hr and 1.6 ± 0.3 ng/24 hr, respectively).2↗ Therefore, urinary 2,3-dinor TXB1 is a suitable marker of thromboxane biosynthesis in rats.
Synonyms 2,3-dinor TXB1
Formal Name 9α,11,15S-trihydroxy-2,3-dinor-thromba-13E-en-1-oic acid
CAS Number 196493-76-2
Molecular Formula C18H32O6
Formula Weight 344.4
Formulation A solution in methyl acetate
Purity>98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES O[C@@H]1[C@H](CCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CCCCC)OC(O)C1 |