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Estradiol
Cayman Chemical Item Number 10006315
Description
Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. It is synthesized from testosterone primarily in the ovarian granulosa cells and placenta, but small amounts can be produced in the adrenal gland.1↗,2↗ Plasma estradiol levels increase gradually between days 1-7 of the menstrual cycle followed by a sharp increase to a peak value of about 300 pg/ml on day 12, just prior to ovulation.3↗,4↗
Synonyms β-Estradiol 17β-Estradiol 17β-Oestradiol E2
Formal Name estra-1,3,5(10)-triene-3,17β-diol
CAS Number 50-28-2
Molecular Formula C18H24O2
Formula Weight 272.4
Formulation A crystalline solid
Purity≥98%
λmax 203, 281 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O[C@H]1CC[C@@]2([H])[C@]([C@]3([H])CC[C@@]21C)([H])CCC4=C3C=CC(O)=C4
InCHI Code 1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InCHI Key VOXZDWNPVJITMN-ZBRFXRBCSA-N |