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Functional Aspects: CD29 antigen is the ß1 subunit that makes up an integrin heterodime. The ß1 subunit associates with one of several alpha subunits that form defined integrin receptors that bind extracellular matrix components such as laminin, collagen, and fibronectin. The integrins are therefore involved with a number of processes including cell migration, wound healing, inflammation and probably cell signaling. This antibody will help detect CD29 and further characterize integrin expression on a variety of tissues. |