产品编号 T1126 | CAS号 9010-34-8 | Sigma Thyroglobulin 来源于猪甲状腺腺体 Thyroglobulin from porcine thyroid gland powder Other Notes Electrophoretically heterogeneous. Preparation Note When reconstituted in water (20 mg/ml), a turbid solution with some insolubles is observed. Biochem/physiol Actions Thyroglobulin has been shown to regulate the transcription of iodide porters including sodium iodide symporter and pendrin. 1 Thyroglobulin is a major protein involved with iodine metabolism. It consists of an iodine-containing protein that is stored in the thyroid gland and is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Thyroglobulin is often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction. form powder mol wt mol wt ~670 kDa composition Iodine, ≥0.3% nitrogen analysis 14.0-17.5% total ash ≤4% isoelectric point 4.58 storage temp. −20°C